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Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo.
Spivak, Anna Yu; Keiser, Jennifer; Vargas, Mireille; Gubaidullin, Rinat R; Nedopekina, Darya A; Shakurova, Elvira R; Khalitova, Rezeda R; Odinokov, Victor N.
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  • Spivak AY; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation.
  • Keiser J; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse, 57, CH-4002 Basel, Switzerland; University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland.
  • Vargas M; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse, 57, CH-4002 Basel, Switzerland; University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland.
  • Gubaidullin RR; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation.
  • Nedopekina DA; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation.
  • Shakurova ER; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation.
  • Khalitova RR; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation.
  • Odinokov VN; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, 450075 Ufa, Russian Federation. Electronic address: odinokov@anrb.ru.
Bioorg Med Chem ; 22(21): 6297-304, 2014 Nov 01.
Article en En | MEDLINE | ID: mdl-25245671
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Schistosoma mansoni / Triterpenos / Esquistosomiasis mansoni / Antihelmínticos Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Schistosoma mansoni / Triterpenos / Esquistosomiasis mansoni / Antihelmínticos Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article