Increased spinal cord Naâº-Kâº-2Clâ» cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain.

Chen, Shao-Rui; Zhu, Lihong; Chen, Hong; Wen, Lei; Laumet, Geoffroy; Pan, Hui-Lin

Increased spinal cord Naâº-Kâº-2Clâ» cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain.

Chen, Shao-Rui; Zhu, Lihong; Chen, Hong; Wen, Lei; Laumet, Geoffroy; Pan, Hui-Lin.

Afiliación

Chen SR; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Zhu L; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Chen H; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Wen L; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Laumet G; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Pan HL; From the Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030 huilinpan@mdanderson.org.

J Biol Chem ; 289(45): 31111-20, 2014 Nov 07.

Article en En | MEDLINE | ID: mdl-25253692

Asunto(s)

Neuralgia/inducido químicamente; Paclitaxel/efectos adversos; Miembro 2 de la Familia de Transportadores de Soluto 12/metabolismo; Sinapsis/metabolismo; Animales; Membrana Celular/efectos de los fármacos; Electrofisiología; Endosomas; Homeostasis; Cinesinas/metabolismo; Masculino; Microtúbulos/efectos de los fármacos; Plasticidad Neuronal; Nocicepción; Ratas; Ratas Sprague-Dawley; Médula Espinal/efectos de los fármacos; Sinapsis/efectos de los fármacos; Moduladores de Tubulina/química

Palabras clave

Chloride Transport; GABA Receptor; Neuroscience; Neurotransmitter; Neurotransmitter Receptor; Pain; Synaptic Plasticity; Trafficking

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sinapsis / Paclitaxel / Miembro 2 de la Familia de Transportadores de Soluto 12 / Neuralgia Límite: Animals Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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