"Multiplexed viability, cytotoxicity, and caspase activity assays".
Methods Mol Biol
; 1219: 21-33, 2015.
Article
en En
| MEDLINE
| ID: mdl-25308259
ABSTRACT
Multiplexed assay chemistries provide for multiple measurements of cellular parameters within a single assay well. This experimental practice is not only more cost efficient, but also provides more information about a compound or treatment. The ability to combine the activity profiles within the same sample provides a level of normalization not possible with parallel assays. Furthermore, multiplexing caspase activity assays with viability and/or cytotoxicity assays can support conclusions regarding cytotoxic mechanism and provide normalization, which may help correct for differences in cell number.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Caspasas
/
Biología Molecular
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Methods Mol Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2015
Tipo del documento:
Article