Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress.

Basile, Giorgia; Leuzzi, Giuseppe; Pichierri, Pietro; Franchitto, Annapaola

Basile, Giorgia; Leuzzi, Giuseppe; Pichierri, Pietro; Franchitto, Annapaola.

Afiliación

Basile G; Section of Molecular Epidemiology, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy Genome Stability Group, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy.
Leuzzi G; Section of Molecular Epidemiology, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy Genome Stability Group, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy.
Pichierri P; Genome Stability Group, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy Section of Experimental and Computational Carcinogenesis, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy.
Franchitto A; Section of Molecular Epidemiology, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy Genome Stability Group, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy annapaola.franchitto@iss.it.

Nucleic Acids Res ; 42(20): 12628-39, 2014 Nov 10.

Article en En | MEDLINE | ID: mdl-25352544

Asunto(s)

Replicación del ADN; Exodesoxirribonucleasas/fisiología; RecQ Helicasas/fisiología; Afidicolina/farmacología; Proteínas de la Ataxia Telangiectasia Mutada/metabolismo; Puntos de Control del Ciclo Celular/genética; Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1); Exodesoxirribonucleasas/genética; Exodesoxirribonucleasas/metabolismo; Genoma; Células HEK293; Humanos; Mutación; Proteínas Quinasas/genética; RecQ Helicasas/genética; RecQ Helicasas/metabolismo; Transducción de Señal; Estrés Fisiológico/genética; Helicasa del Síndrome de Werner

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Replicación del ADN / Exodesoxirribonucleasas / RecQ Helicasas Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2014 Tipo del documento: Article País de afiliación: Italia

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