Ventilatory efficiency before and after lung volume reduction surgery.
Respir Care
; 60(1): 63-71, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25371397
BACKGROUND: Lung volume reduction surgery (LVRS) has been shown to improve the clearance of carbon dioxide and minute ventilation (VÌE) in select patients with COPD. One variable often assessed in COPD is ventilatory efficiency (VÌE/VÌCO2 ). METHODS: We compared 55 LVRS subjects with 25 controls from the National Emphysema Treatment Trial. VÌE/VÌCO2 was calculated from cardiopulmonary exercise testing at baseline and 6-months. We sought to assess VÌE/VÌCO2 changes with LVRS compared with controls who only received standard medical care. RESULTS: At 6 months, the LVRS group significantly increased peak VÌO2 , work load, VÌE, VÌCO2 , and tidal volume while lowering peak and lowest VÌE/VÌCO2 (improved ventilatory efficiency) and end-tidal carbon dioxide pressure. The control group did not display these changes. The changes were greatest in the LVRS subjects who improved their exercise capacity after surgery (> 10 W). CONCLUSIONS: The changes were greatest in the LVRS subjects who showed the most functional improvement, indicating an association of improved ventilation with improved functional outcome.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neumonectomía
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Intercambio Gaseoso Pulmonar
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Tolerancia al Ejercicio
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Ventilación Pulmonar
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Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Respir Care
Año:
2015
Tipo del documento:
Article