Nanotheragnostic applications for ischemic and hemorrhagic strokes: improved delivery for a better prognosis.
Curr Neurol Neurosci Rep
; 15(1): 505, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25394858
ABSTRACT
Stroke is the second leading cause of death worldwide and a major cause of long-term severe disability representing a global health burden and one of the highly researched medical conditions. Nanostructured material synthesis and engineering have been recently developed and have been largely integrated into many fields including medicine. Recent studies have shown that nanoparticles might be a valuable tool in stroke. Different types, shapes, and sizes of nanoparticles have been used for molecular/biomarker profiling and imaging to help in early diagnosis and prevention of stroke and for drug/RNA delivery for improved treatment and neuroprotection. However, these promising applications have limitations, including cytotoxicity, which hindered their adoption into clinical use. Future research is warranted to fully develop and effectively and safely translate nanoparticles for stroke diagnosis and treatment into the clinic. This work will discuss the emerging role of nanotheragnostics in stroke diagnosis and treatment applications.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Accidente Cerebrovascular
/
Nanopartículas
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
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Screening_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Neurol Neurosci Rep
Asunto de la revista:
NEUROLOGIA
Año:
2015
Tipo del documento:
Article