Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.

Chow, I-Ting; Yang, Junbao; Gates, Theresa J; James, Eddie A; Mai, Duy T; Greenbaum, Carla; Kwok, William W

Chow, I-Ting; Yang, Junbao; Gates, Theresa J; James, Eddie A; Mai, Duy T; Greenbaum, Carla; Kwok, William W.

Afiliación

Chow IT; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
Yang J; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
Gates TJ; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
James EA; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
Mai DT; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
Greenbaum C; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America.
Kwok WW; Benaroya Research Institute at Virginia Mason, Seattle, WA, United States of America; Department of Medicine, University of Washington, Seattle, WA, United States of America.

PLoS One ; 9(11): e112882, 2014.

Article en En | MEDLINE | ID: mdl-25405480

Asunto(s)

Linfocitos T CD4-Positivos/inmunología; Diabetes Mellitus Tipo 1/fisiopatología; Glutamato Descarboxilasa/efectos adversos; Antígenos HLA-DQ/genética; Diabetes Mellitus Tipo 1/inmunología; Glutamato Descarboxilasa/metabolismo; Humanos; Estadísticas no Paramétricas; Washingtón

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Antígenos HLA-DQ / Diabetes Mellitus Tipo 1 / Glutamato Descarboxilasa Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

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