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SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis.
Dillenburg-Pilla, Patricia; Patel, Vyomesh; Mikelis, Constantinos M; Zárate-Bladés, Carlos Rodrigo; Doçi, Colleen L; Amornphimoltham, Panomwat; Wang, Zhiyong; Martin, Daniel; Leelahavanichkul, Kantima; Dorsam, Robert T; Masedunskas, Andrius; Weigert, Roberto; Molinolo, Alfredo A; Gutkind, J Silvio.
Afiliación
  • Dillenburg-Pilla P; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Patel V; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Mikelis CM; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Zárate-Bladés CR; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Doçi CL; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Amornphimoltham P; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Wang Z; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Martin D; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Leelahavanichkul K; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Dorsam RT; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Masedunskas A; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Weigert R; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Molinolo AA; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland.
  • Gutkind JS; *Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, and Laboratory of Immunology, National Eye Institute, U. S. National Institutes of Health, Bethesda, Maryland sg39v@nih.gov.
FASEB J ; 29(3): 1056-68, 2015 Mar.
Article en En | MEDLINE | ID: mdl-25466898
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Movimiento Celular / Neoplasias del Cuello Uterino / Receptores CXCR4 / Complejos Multiproteicos / Subunidad alfa de la Proteína de Unión al GTP Gi2 / Quimiocina CXCL12 / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2015 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Movimiento Celular / Neoplasias del Cuello Uterino / Receptores CXCR4 / Complejos Multiproteicos / Subunidad alfa de la Proteína de Unión al GTP Gi2 / Quimiocina CXCL12 / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2015 Tipo del documento: Article