Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury.

Chen, Chien-Cheng; Hung, Tai-Ho; Lee, Chao Yu; Wang, Liang-Fei; Wu, Chun-Hu; Ke, Chia-Hua; Chen, Szu-Fu

Chen, Chien-Cheng; Hung, Tai-Ho; Lee, Chao Yu; Wang, Liang-Fei; Wu, Chun-Hu; Ke, Chia-Hua; Chen, Szu-Fu.

Afiliación

Chen CC; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, Republic of China.
Hung TH; Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Taipei and College of Medicine, Chang Gung University, Taipei, Taiwan, Republic of China.
Lee CY; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, Republic of China.
Wang LF; Departments of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, Republic of China; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Wu CH; Departments of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, Republic of China; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Ke CH; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, Republic of China; Departments of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Chen SF; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, Republic of China; Departments of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, Republic of China.

PLoS One ; 9(12): e115694, 2014.

Article en En | MEDLINE | ID: mdl-25546475

Asunto(s)

Berberina/uso terapéutico; Lesiones Encefálicas/prevención & control; Neuroglía/metabolismo; Fármacos Neuroprotectores/uso terapéutico; Animales; Apoptosis; Berberina/farmacología; Barrera Hematoencefálica/efectos de los fármacos; Barrera Hematoencefálica/metabolismo; Lesiones Encefálicas/fisiopatología; Células Cultivadas; Quimiocinas/genética; Quimiocinas/metabolismo; Quinasas MAP Reguladas por Señal Extracelular/metabolismo; Inflamación/tratamiento farmacológico; Masculino; Ratones; Ratones Endogámicos C57BL; Factor 88 de Diferenciación Mieloide/genética; Factor 88 de Diferenciación Mieloide/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Neuroglía/efectos de los fármacos; Neuronas/efectos de los fármacos; Neuronas/metabolismo; Fármacos Neuroprotectores/farmacología; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal; Receptor Toll-Like 4/genética; Receptor Toll-Like 4/metabolismo

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Berberina / Lesiones Encefálicas / Neuroglía / Fármacos Neuroprotectores Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: China

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