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An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Van Overbeke, Wouter; Wongsantichon, Jantana; Everaert, Inge; Verhelle, Adriaan; Zwaenepoel, Olivier; Loonchanta, Anantasak; Burtnick, Leslie D; De Ganck, Ariane; Hochepied, Tino; Haigh, Jody; Cuvelier, Claude; Derave, Wim; Robinson, Robert C; Gettemans, Jan.
Afiliación
  • Van Overbeke W; Department of Biochemistry, Faculty of Medicine and Health Sciences.
  • Wongsantichon J; Institute of Molecular and Cellular Biology, A*STAR, Biopolis, Singapore 138673, Singapore.
  • Everaert I; Department of Movement and Sport Sciences, Faculty of Medicine and Health Sciences.
  • Verhelle A; Department of Biochemistry, Faculty of Medicine and Health Sciences.
  • Zwaenepoel O; Department of Biochemistry, Faculty of Medicine and Health Sciences.
  • Loonchanta A; Department of Chemistry and Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
  • Burtnick LD; Department of Chemistry and Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
  • De Ganck A; Department of Biochemistry, Faculty of Medicine and Health Sciences.
  • Hochepied T; Department for Molecular Biomedical Research, VIB, Ghent, Belgium, Department of Biomedical Molecular Biology and.
  • Haigh J; Department of Biomedical Molecular Biology and Vascular Cell Biology Unit, VIB Inflammation Research Centre, Ghent, Belgium and Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred
  • Cuvelier C; Department of Pathology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
  • Derave W; Department of Movement and Sport Sciences, Faculty of Medicine and Health Sciences.
  • Robinson RC; Institute of Molecular and Cellular Biology, A*STAR, Biopolis, Singapore 138673, Singapore, Department of Biochemistry, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore, jan.gettemans@ugent.be rrobinson@imcb.a-star.edu.sg.
  • Gettemans J; Department of Biochemistry, Faculty of Medicine and Health Sciences, jan.gettemans@ugent.be rrobinson@imcb.a-star.edu.sg.
Hum Mol Genet ; 24(9): 2492-507, 2015 May 01.
Article en En | MEDLINE | ID: mdl-25601851
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gelsolina / Amiloidosis Familiar / Retículo Endoplásmico / Anticuerpos de Dominio Único / Amiloide Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gelsolina / Amiloidosis Familiar / Retículo Endoplásmico / Anticuerpos de Dominio Único / Amiloide Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article