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Cup-like blasts in acute myeloid leukemia.
Jost, Edgar; Herwartz, Reinhild; Hoß, Mareike; Vankann, Lucia; Fuchs, Roland.
Afiliación
  • Jost E; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
  • Herwartz R; Electron Microscopic Facility, Medical Faculty, RWTH Aachen University, Aachen, Germany.
  • Hoß M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
  • Vankann L; Electron Microscopic Facility, Medical Faculty, RWTH Aachen University, Aachen, Germany.
  • Fuchs R; Medical Faculty, Institute for Pathology, RWTH Aachen University, Aachen, Germany.
Am J Hematol ; 90(9): 847-8, 2015 Sep.
Article en En | MEDLINE | ID: mdl-25615838
ABSTRACT
A patient with AML with normal karyotype and the cytological pattern of cup-like blasts (CLB) is reported. The typical morphology on Pappenheim stained blood smears is shown. In addition transmission electron microscopy pictures demonstrate impressively the invaginated nuclear pocket compressing the chromatin. Cup-like blasts usually do not express CD34. There is a close relationship of CLB-AML with the molecular aberrations of NPM1 and/or FLT3-ITD.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células de la Médula Ósea / Leucemia Mieloide Aguda / Núcleo Celular Límite: Aged80 / Female / Humans Idioma: En Revista: Am J Hematol Año: 2015 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células de la Médula Ósea / Leucemia Mieloide Aguda / Núcleo Celular Límite: Aged80 / Female / Humans Idioma: En Revista: Am J Hematol Año: 2015 Tipo del documento: Article País de afiliación: Alemania