SIRT5 regulation of ammonia-induced autophagy and mitophagy.

Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco

Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco.

Afiliación

Polletta L; a Department of Experimental Medicine ; University of Rome ; Sapienza ; Rome , Italy.

Autophagy ; 11(2): 253-70, 2015.

Article en En | MEDLINE | ID: mdl-25700560

Asunto(s)

Amoníaco/farmacología; Autofagia/efectos de los fármacos; Mitocondrias/efectos de los fármacos; Mitofagia/efectos de los fármacos; Sirtuinas/metabolismo; Autofagia/fisiología; Glutaminasa/metabolismo; Humanos; Mitocondrias/metabolismo; Mitofagia/fisiología; Proteolisis/efectos de los fármacos; Ubiquitina-Proteína Ligasas/metabolismo

Palabras clave

ACTB, actin, ß; ATG, autophagy-related; BNIP3, BCL2/adenovirus E1B 19kDa interacting protein 3; BPTES, bis-2-(5-phenylacetamido-1, 3, 4-thiadiazol-2-yl)ethyl sulfide; COX4I1, cytochrome c oxidase subunit IV isoform 1; CPS1, carbamoyl-phosphate synthase 1, mitochondrial; GABARAP, GABA(A) receptor-associated protein; GABARAPL2, GABA(A) receptor-associated protein-like 2; GLS, glutaminase; GLUD1, glutamate dehydrogenase 1; GLUL, glutamate-ammonia ligase; MAP1LC3B, microtubule-associated protein 1 light chain 3 ß; MFN2, mitofusin 2; OPA1, optic atrophy 1 (autosomal dominant); PARK2, parkin RBR E3 ubiquitin protein ligase; PEG, polyethylene glycol; PINK1, PTEN induced putative kinase 1; SIRT5, sirtuin 5; SQSTM1, sequestosome 1; TCA, tricarboxylic acid cycle; TEM, transmission electron microscopy; ammonia; autophagy; glutaminase; glutamine; hexachlorophene, 2, 2'-methylenebis(3, 4, 6-trichlorophenol); mitochondrial dynamics; mitophagy; molecular rehabilitation; sirtuin 5; succinylation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Sirtuinas / Mitofagia / Amoníaco / Mitocondrias Límite: Humans Idioma: En Revista: Autophagy Año: 2015 Tipo del documento: Article País de afiliación: Italia

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