Metal-free synthesis of indole via NIS-mediated cascade C-N bond formation/aromatization.
J Org Chem
; 80(8): 3841-51, 2015 Apr 17.
Article
en En
| MEDLINE
| ID: mdl-25785554
ABSTRACT
A novel rapid synthesis of indoles from N-Ts-2-alkenylanilines has been described; the reaction involves a NIS-mediated cascade C-N bond formation/aromatization, and a series of indoles with various functional groups have been synthesized in good to excellent yields under mild conditions without any other additives or catalysts.
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1
Bases de datos:
MEDLINE
Asunto principal:
Indoles
/
Compuestos de Anilina
/
Metales
Idioma:
En
Revista:
J Org Chem
Año:
2015
Tipo del documento:
Article