MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death.

Chaudhuri, Amrita Datta; Kabaria, Savan; Choi, Doo Chul; Mouradian, M Maral; Junn, Eunsung

Chaudhuri, Amrita Datta; Kabaria, Savan; Choi, Doo Chul; Mouradian, M Maral; Junn, Eunsung.

Afiliación

Chaudhuri AD; From the Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854.
Kabaria S; From the Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854.
Choi DC; From the Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854.
Mouradian MM; From the Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854.
Junn E; From the Center for Neurodegenerative and Neuroimmunologic Diseases, Department of Neurology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 junneu@rwjms.rutgers.edu.

J Biol Chem ; 290(19): 12425-34, 2015 May 08.

Article en En | MEDLINE | ID: mdl-25814668

Asunto(s)

1-Metil-4-fenilpiridinio/química; Muerte Celular; MicroARNs/metabolismo; Factor de Transcripción ReIA/metabolismo; Adenosina Trifosfato/química; Animales; Diferenciación Celular; Línea Celular Tumoral; Supervivencia Celular; Desoxiglucosa/química; Glucosa/química; Transportador de Glucosa de Tipo 3/metabolismo; Glucólisis; Células HEK293; Humanos; Ácido Láctico/química; Ratones; Ratones Endogámicos C57BL; Mitocondrias/metabolismo; Neuronas/metabolismo; Fosforilación Oxidativa; Oxígeno/química; Enfermedad de Parkinson/metabolismo; Fosforilación

Palabras clave

1-methyl-4-phenylpyridinium; NF-kappa B (NF-KB); Parkinson disease; RelA; glycolysis; microRNA (miRNA); microRNA-7; neurodegenerative disease

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: 1-Metil-4-fenilpiridinio / Muerte Celular / MicroARNs / Factor de Transcripción ReIA Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

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