Homeostatic control of biological membranes by dedicated lipid and membrane packing sensors.
Biol Chem
; 396(9-10): 1043-58, 2015 Sep.
Article
en En
| MEDLINE
| ID: mdl-25849795
ABSTRACT
Biological membranes are dynamic and complex assemblies of lipids and proteins. Eukaryotic lipidomes encompass hundreds of distinct lipid species and we have only begun to understand their role and function. This review focuses on recent advances in the field of lipid sensors and discusses methodical approaches to identify and characterize putative sensor domains. We elaborate on the role of integral and conditionally membrane-associated sensor proteins, their molecular mechanisms, and identify open questions in the emerging field of membrane homeostasis.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Membrana Celular
/
Homeostasis
/
Lípidos de la Membrana
/
Proteínas de la Membrana
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biol Chem
Asunto de la revista:
BIOQUIMICA
Año:
2015
Tipo del documento:
Article