[Prévalence de l'infection à Helicobacter pylori et des lésions endoscopiques hautes chez les diabétiques: Etude cas/témoins]. / Prevalence of helicobacter pylori infection and gastroscopic finding in diabetic patients: a case-control study.

ABSTRACT

BACKGROUND: Current data on the prevalence of Helicobacter pylori infection in dyspeptic diabetic patients are contradictory in the literature. AIM: the aim was to assess the prevalence of Helicobacter pylori infection, gastroscopic lesions, and gastric histopathological lesions, in dyspeptic diabetic patients. METHODS: It was a case-control study collecting 394 dyspeptic patients (194 diabetic and 200 nondiabetic patients). RESULTS: The average age of patients was 47 years. 144 patients (47%) were male and 150 patients (53%) were female. The two patient groups were matched for age and sex. The prevalence of Helicobacter pylori infection was comparable between the two groups of patients (85% in diabetics versus 90% in the controls). The frequency of gastroscopic lesions was 50% in diabetics and 55% in controls with no significant difference between the two groups. At histology, the prevalence of chronic gastritis, intestinal metaplasia, and gastric atrophy was 85%, 13% and 39% respectively in the group of diabetic patients. These results were comparable to those found in patients without diabetes. CONCLUSION: Our work shows no difference between diabetics and non-diabetics on the prevalence of Helicobacter pylori infection, gastroscopic, and gastric histopathological lesions.