Maternal serum markers, characteristics and morbidly adherent placenta in women with previa.
J Perinatol
; 35(8): 570-4, 2015 Aug.
Article
en En
| MEDLINE
| ID: mdl-25927270
ABSTRACT
OBJECTIVE:
To examine associations with morbidly adherent placenta (MAP) among women with placenta previa. STUDYDESIGN:
Women with MAP (cases) and previa alone (controls) were identified from a cohort of 236,714 singleton pregnancies with both first and second trimester prenatal screening, and live birth and hospital discharge records; pregnancies with aneuploidies and neural tube or abdominal wall defects were excluded. Logistic binomial regression was used to compare cases with controls.RESULT:
In all, 37 cases with MAP and 699 controls with previa alone were included. Risk for MAP was increased among multiparous women with pregnancy-associated plasma protein-A (PAPP-A) ⩾95th percentile (⩾2.63 multiple of the median (MoM); adjusted OR (aOR) 8.7, 95% confidence interval (CI) 2.8 to 27.4), maternal-serum alpha fetoprotein (MS-AFP) ⩾95th percentile (⩾1.79 MoM; aOR 2.8, 95% CI 1.0 to 8.0), and 1 and ⩾2 prior cesarean deliveries (CDs; aORs 4.4, 95% CI 1.5 to 13.6 and 18.4, 95% CI 5.9 to 57.5, respectively).CONCLUSION:
Elevated PAPP-A, elevated MS-AFP and prior CDs are associated with MAP among women with previa.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Placenta Accreta
/
Placenta Previa
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Proteína Plasmática A Asociada al Embarazo
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Complicaciones del Embarazo
/
Biomarcadores
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
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Adult
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Female
/
Humans
/
Pregnancy
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos