Protection against T1DM-Induced Bone Loss by Zinc Supplementation: Biomechanical, Histomorphometric, and Molecular Analyses in STZ-Induced Diabetic Rats.

Bortolin, Raul Hernandes; da Graça Azevedo Abreu, Bento João; Abbott Galvão Ururahy, Marcela; Costa de Souza, Karla Simone; Bezerra, João Felipe; Loureiro, Melina Bezerra; da Silva, Flávio Santos; Marques, Dáfiny Emanuele da Silva; Batista, Angélica Amanda de Sousa; Oliveira, Gisele; Luchessi, André Ducati; Lima, Valéria Morgiana Gualberto Duarte Moreira; Miranda, Carlos Eduardo Saraiva; Lia Fook, Marcus Vinicius; Almeida, Maria das Graças; de Rezende, Luciana Augusto; de Rezende, Adriana Augusto

Bortolin, Raul Hernandes; da Graça Azevedo Abreu, Bento João; Abbott Galvão Ururahy, Marcela; Costa de Souza, Karla Simone; Bezerra, João Felipe; Loureiro, Melina Bezerra; da Silva, Flávio Santos; Marques, Dáfiny Emanuele da Silva; Batista, Angélica Amanda de Sousa; Oliveira, Gisele; Luchessi, André Ducati; Lima, Valéria Morgiana Gualberto Duarte Moreira; Miranda, Carlos Eduardo Saraiva; Lia Fook, Marcus Vinicius; Almeida, Maria das Graças; de Rezende, Luciana Augusto; de Rezende, Adriana Augusto.

Afiliación

Bortolin RH; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
da Graça Azevedo Abreu BJ; Department of Morphology, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Abbott Galvão Ururahy M; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Costa de Souza KS; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Bezerra JF; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Loureiro MB; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
da Silva FS; Department of Morphology, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Marques DE; Department of Morphology, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Batista AA; Department of Chemistry, University of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
Oliveira G; Department of Chemistry, University of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
Luchessi AD; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Lima VM; Department of Pharmacy, State University of Paraiba, Campina Grande, Paraiba, Brazil.
Miranda CE; Department of Pharmacy, University of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
Lia Fook MV; Laboratory of Evaluation and Development of Biomaterials, Federal University of Campina Grande, Campina Grande, Paraiba, Brazil.
Almeida Md; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
de Rezende LA; Department of Chemistry, University of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
de Rezende AA; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

PLoS One ; 10(5): e0125349, 2015.

Article en En | MEDLINE | ID: mdl-25933189

Asunto(s)

Densidad Ósea/efectos de los fármacos; Resorción Ósea/prevención & control; Diabetes Mellitus Experimental/dietoterapia; Suplementos Dietéticos; ARN Mensajero/genética; Zinc/administración & dosificación; Animales; Fenómenos Biomecánicos; Colágeno Tipo I/genética; Colágeno Tipo I/metabolismo; Cadena alfa 1 del Colágeno Tipo I; Diabetes Mellitus Experimental/inducido químicamente; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/patología; Diabetes Mellitus Tipo 1/dietoterapia; Diabetes Mellitus Tipo 1/genética; Diabetes Mellitus Tipo 1/patología; Módulo de Elasticidad; Fémur/efectos de los fármacos; Fémur/metabolismo; Fémur/patología; Regulación de la Expresión Génica; Humanos; Masculino; Metaloproteinasa 9 de la Matriz/genética; Metaloproteinasa 9 de la Matriz/metabolismo; Osteocalcina/genética; Osteocalcina/metabolismo; Osteoprotegerina/genética; Osteoprotegerina/metabolismo; ARN Mensajero/metabolismo; Ratas; Ratas Wistar; Estreptozocina; Tibia/efectos de los fármacos; Tibia/metabolismo; Tibia/patología

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Zinc / Resorción Ósea / ARN Mensajero / Densidad Ósea / Suplementos Dietéticos / Diabetes Mellitus Experimental Tipo de estudio: Prognostic_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Brasil

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