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KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.
Leiser, Dominic; Medová, Michaela; Mikami, Kei; Nisa, Lluís; Stroka, Deborah; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel M; Zimmer, Yitzhak.
Afiliación
  • Leiser D; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Medová M; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Mikami K; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Nisa L; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Stroka D; Department of Visceral Surgery, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Blaukat A; Merck Serono an Affiliate of Merck Serono Research & Development, Merck KGaA, 64271 Darmstadt, Germany.
  • Bladt F; Merck Serono an Affiliate of Merck Serono Research & Development, Merck KGaA, 64271 Darmstadt, Germany.
  • Aebersold DM; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
  • Zimmer Y; Department of Radiation Oncology, Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Switzerland. Electronic address: yitzhak.zimmer@insel.ch.
Mol Oncol ; 9(7): 1434-46, 2015 Aug.
Article en En | MEDLINE | ID: mdl-25933688

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genes ras / Proteínas Proto-Oncogénicas c-met / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Suiza

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genes ras / Proteínas Proto-Oncogénicas c-met / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Suiza