Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.
Autophagy
; 11(5): 769-84, 2015.
Article
en En
| MEDLINE
| ID: mdl-25945613
Palabras clave
ATP6V0D1, ATPase H+ transporting lysosomal 38kDa, V0 subunit d1; Baf, bafilomycin A1; CAV1, caveolin 1; CHO, water-soluble cholesterol; CQ, choloroquine; CTSL, cathepsin L; CTxB, cholera toxin subunit B; DRF, detergent-resistant fraction; DSF, detergent-soluble fraction; EGF, epidermal growth factor; KO, knockout; LAMP1, lysosomal-associated membrane protein 1; MAP1LC3/LC3, microtubule-associated protein 1 light chain 3; MBCD, methyl-ß-cyclodextrin; MEF, mouse embryonic fibroblasts; MTOR, mechanistic target of rapamycin; PBS, phosphate-buffered saline; PI, propidium iodide; PLA, proximity ligation assay; PTRF, polymerase I and transcript release factor; TFRC, transferrin receptor; TSC, tuberous sclerosis complex; WT, wild type.; autophagy; breast cancer; caveolin 1; lipid rafts; lysosome; tfLC3B, mRFP-GFP tandem fluorescent-tagged LC3B
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Autofagia
/
Estrés Fisiológico
/
Neoplasias de la Mama
/
Caveolina 1
/
Lisosomas
Tipo de estudio:
Prognostic_studies
Límite:
Animals
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Female
/
Humans
Idioma:
En
Revista:
Autophagy
Año:
2015
Tipo del documento:
Article