Gambierone, a Ladder-Shaped Polyether from the Dinoflagellate Gambierdiscus belizeanus.
Org Lett
; 17(10): 2392-5, 2015 May 15.
Article
en En
| MEDLINE
| ID: mdl-25950201
ABSTRACT
A new natural product named gambierone (1) was isolated from the cultured dinoflagellate Gambierdiscus belizeanus. The structure of this compound features an unprecedented polyether skeleton and an unusual right-hand side chain. Its relative configuration was fully determined by interpretation of ROESY experiment and comparison between experimental and theoretical NMR data. Although the succession of cycles has no chemical similarity with ciguatoxins, 1 has a molecular formula and biological activity similar to those of CTX-3C, although much lower in intensity.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Dinoflagelados
/
Éteres
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
España