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A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates.
Chichili, Gurunadh R; Huang, Ling; Li, Hua; Burke, Steve; He, Leilei; Tang, Qin; Jin, Linda; Gorlatov, Sergey; Ciccarone, Valentina; Chen, Francine; Koenig, Scott; Shannon, Michele; Alderson, Ralph; Moore, Paul A; Johnson, Syd; Bonvini, Ezio.
Afiliación
  • Chichili GR; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Huang L; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Li H; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Burke S; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • He L; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Tang Q; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Jin L; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Gorlatov S; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Ciccarone V; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Chen F; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Koenig S; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Shannon M; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Alderson R; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Moore PA; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Johnson S; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA.
  • Bonvini E; MacroGenics Inc., 9640 Medical Center Drive, Rockville, MD 20850, USA. bonvinie@macrogenics.com.
Sci Transl Med ; 7(289): 289ra82, 2015 May 27.
Article en En | MEDLINE | ID: mdl-26019218
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos T / Leucemia Mieloide Aguda / Complejo CD3 / Subunidad alfa del Receptor de Interleucina-3 Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos T / Leucemia Mieloide Aguda / Complejo CD3 / Subunidad alfa del Receptor de Interleucina-3 Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos