[Molecular-genetic mechanisms of cornea morphogenesis].
Izv Akad Nauk Ser Biol
; (2): 117-26, 2015.
Article
en Ru
| MEDLINE
| ID: mdl-26021153
ABSTRACT
In this paper, we analyzed our own results and published data on the expression of regulatory genes encoding transcription factors Pax6/PAX6, Pitx2/PITX2, Fox1/FOXC1, Prox1/PROX1, Oct4/OCT4, Nanog/NANOG, and TGFß2 signaling protein during morphogenesis of the cornea in vertebrates. We considered the results obtained for the cornea of model animals, primarily mice, and human fetal cornea. The main possibility of establishing common mechanisms of eye development in vertebrates in health and disease is comparative studies of eye morphogenesis of humans and animal models.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Regulación del Desarrollo de la Expresión Génica
/
Córnea
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
Ru
Revista:
Izv Akad Nauk Ser Biol
Asunto de la revista:
BIOLOGIA
Año:
2015
Tipo del documento:
Article