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Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Zuckermann, Marc; Hovestadt, Volker; Knobbe-Thomsen, Christiane B; Zapatka, Marc; Northcott, Paul A; Schramm, Kathrin; Belic, Jelena; Jones, David T W; Tschida, Barbara; Moriarity, Branden; Largaespada, David; Roussel, Martine F; Korshunov, Andrey; Reifenberger, Guido; Pfister, Stefan M; Lichter, Peter; Kawauchi, Daisuke; Gronych, Jan.
Afiliación
  • Zuckermann M; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Hovestadt V; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Knobbe-Thomsen CB; 1] Department of Neuropathology, Heinrich Heine University Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany [2] German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, 40225 Düsseldorf, Germany.
  • Zapatka M; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Northcott PA; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Schramm K; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Belic J; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Jones DT; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Tschida B; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Moriarity B; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Largaespada D; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Roussel MF; Tumor Cell Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.
  • Korshunov A; 1] Department of Neuropathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany [2] Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 220-221, 69120 Heidelberg, Germany.
  • Reifenberger G; 1] Department of Neuropathology, Heinrich Heine University Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany [2] German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, 40225 Düsseldorf, Germany.
  • Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Lichter P; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Kawauchi D; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Gronych J; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Nat Commun ; 6: 7391, 2015 Jun 11.
Article en En | MEDLINE | ID: mdl-26067104
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Modelos Animales de Enfermedad / Técnicas de Inactivación de Genes / Sistemas CRISPR-Cas / Meduloblastoma Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Modelos Animales de Enfermedad / Técnicas de Inactivación de Genes / Sistemas CRISPR-Cas / Meduloblastoma Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Alemania