Cerebral autoregulation in pregnancies complicated by diabetes and overweight.
Diab Vasc Dis Res
; 12(5): 377-80, 2015 Sep.
Article
en En
| MEDLINE
| ID: mdl-26092823
ABSTRACT
AIM:
The aim of this study was to estimate the impact of diabetes and obesity on cerebral autoregulation in pregnancy.METHODS:
Cerebral autoregulation was evaluated in women with gestational diabetes, type 2 diabetes mellitus and/or overweight (body mass index ⩾ 25 kg m(-2)) and compared to a cohort of euglycaemic pregnant women. The autoregulation index was calculated using simultaneously recorded cerebral blood flow velocity in the middle cerebral artery and blood pressure. Autoregulation index values of 0 and 9 indicate absent and perfect autoregulation, respectively.RESULTS:
Autoregulation index in women with either diabetes (n = 33, 6.6 ± 1.1) or overweight (n = 21, 6.7 ± 0.6) was not significantly different to that in control patients (n = 23, 6.6 ± 0.8, p = 0.96).CONCLUSION:
Cerebral autoregulation is not impaired in pregnant women who have non-vasculopathic diabetes or overweight. This suggests that the increased risk of pre-eclampsia in diabetic and overweight women is not associated with early impaired cerebral autoregulation.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Presión Sanguínea
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Encéfalo
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Diabetes Gestacional
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Diabetes Mellitus Tipo 2
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Sobrepeso
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Homeostasis
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
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Pregnancy
Idioma:
En
Revista:
Diab Vasc Dis Res
Asunto de la revista:
ANGIOLOGIA
/
ENDOCRINOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos