New Anthocyanin-Human Salivary Protein Complexes.
Langmuir
; 31(30): 8392-401, 2015 Aug 04.
Article
en En
| MEDLINE
| ID: mdl-26162056
ABSTRACT
The interaction between phenolic compounds and salivary proteins is considered the basis of the poorly understood phenomenon of astringency. Furthermore, this interaction is an important factor in relation to their bioavailability. In this work, interactions between anthocyanin and human salivary protein fraction were studied by mass spectrometry (MALDI-TOF-MS and FIA-ESI-MS) and saturation-transfer difference (STD) NMR spectroscopy. Anthocyanins were able to interact with saliva proteins. The dissociation constant (KD) between malvidin 3-glucoside and salivary proline-rich proteins was 1.92 mM for the hemiketal form (pH 3.4) and 1.83 mM for the flavylium cation (pH 1.0). New soluble complexes between these salivary proteins and malvidin 3-glucoside were identified for the first time.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Proteínas y Péptidos Salivales
/
Antocianinas
Tipo de estudio:
Prognostic_studies
Límite:
Adult
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Female
/
Humans
/
Male
Idioma:
En
Revista:
Langmuir
Asunto de la revista:
QUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Portugal