Antibacterial Δ(1) -3-ketosteroids from the South China Sea gorgonian coral Subergorgia rubra.
Chem Biodivers
; 12(7): 1068-74, 2015 Jul.
Article
en En
| MEDLINE
| ID: mdl-26172327
ABSTRACT
Three new Δ(1) -3-ketosteroids characterized with a 9-OH, subergosterones A-C (1-3), together with five known analogs 4-8, were obtained from the gorgonian coral Subergorgia rubra collected from the South China Sea. The structures of 1-3, including their absolute configurations, were determined by comprehensive spectroscopic methods and electronic circular dichroism (ECD) experiments. Compounds 2 and 3 exhibited inhibitory antibacterial activities against Bacillus cereus with MIC values of 1.56â
µM.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Bacillus cereus
/
Antozoos
/
Cetosteroides
/
Antibacterianos
Límite:
Animals
Idioma:
En
Revista:
Chem Biodivers
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2015
Tipo del documento:
Article