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Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes.
Jane-wit, Dan; Surovtseva, Yulia V; Qin, Lingfeng; Li, Guangxin; Liu, Rebecca; Clark, Pamela; Manes, Thomas D; Wang, Chen; Kashgarian, Michael; Kirkiles-Smith, Nancy C; Tellides, George; Pober, Jordan S.
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  • Jane-wit D; Division of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06520;
  • Surovtseva YV; Yale Center for Molecular Discovery, Yale University, New Haven, CT 06516;
  • Qin L; Department of Surgery, Yale University School of Medicine, New Haven, CT 06520;
  • Li G; Department of Surgery, Yale University School of Medicine, New Haven, CT 06520;
  • Liu R; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Clark P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Manes TD; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Wang C; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Kashgarian M; Department of Pathology, Yale University School of Medicine, New Haven, CT 06520.
  • Kirkiles-Smith NC; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Tellides G; Department of Surgery, Yale University School of Medicine, New Haven, CT 06520;
  • Pober JS; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520; Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 jordan.pober@yale.edu.
Proc Natl Acad Sci U S A ; 112(31): 9686-91, 2015 Aug 04.
Article en En | MEDLINE | ID: mdl-26195760
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Endosomas / Transducción de Señal / Complejo de Ataque a Membrana del Sistema Complemento / FN-kappa B / Proteínas Serina-Treonina Quinasas / Proteínas de Unión al GTP rab5 / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Endosomas / Transducción de Señal / Complejo de Ataque a Membrana del Sistema Complemento / FN-kappa B / Proteínas Serina-Treonina Quinasas / Proteínas de Unión al GTP rab5 / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article