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Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy.
Tedeschi, Philip M; Lin, HongXia; Gounder, Murugesan; Kerrigan, John E; Abali, Emine Ercikan; Scotto, Kathleen; Bertino, Joseph R.
Afiliación
  • Tedeschi PM; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Lin H; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Gounder M; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Kerrigan JE; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Abali EE; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Scotto K; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey.
  • Bertino JR; Departments of Pharmacology and Medicine, Rutgers Cancer Institute of New Jersey (P.M.T., H.L., M.G., J.E.K., K.S., J.R.B.), and Department of Biochemistry (E.E.A.), Rutgers University, New Brunswick, New Jersey bertinoj@cinj.rutgers.edu.
Mol Pharmacol ; 88(4): 720-7, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26219913
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Niacinamida / Estrés Oxidativo / Citosol / NADP / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Mol Pharmacol Año: 2015 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Niacinamida / Estrés Oxidativo / Citosol / NADP / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Mol Pharmacol Año: 2015 Tipo del documento: Article