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Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution.
Ewing, Adam D; Gacita, Anthony; Wood, Laura D; Ma, Florence; Xing, Dongmei; Kim, Min-Sik; Manda, Srikanth S; Abril, Gabriela; Pereira, Gavin; Makohon-Moore, Alvin; Looijenga, Leendert H J; Gillis, Ad J M; Hruban, Ralph H; Anders, Robert A; Romans, Katharine E; Pandey, Akhilesh; Iacobuzio-Donahue, Christine A; Vogelstein, Bert; Kinzler, Kenneth W; Kazazian, Haig H; Solyom, Szilvia.
Afiliación
  • Ewing AD; Mater Research Institute, University of Queensland, Woolloongabba, Queensland 4102, Australia;
  • Gacita A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Wood LD; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Ma F; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Xing D; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Kim MS; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Manda SS; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Abril G; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Pereira G; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Makohon-Moore A; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Looijenga LH; Department of Pathology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands;
  • Gillis AJ; Department of Pathology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands;
  • Hruban RH; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Anders RA; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Romans KE; The Johns Hopkins University School of Medicine Cancer Biology, Baltimore, Maryland 21205, USA;
  • Pandey A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Iacobuzio-Donahue CA; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA;
  • Vogelstein B; The Ludwig Center and The Howard Hughes Medical Institute at Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland 21287, USA.
  • Kinzler KW; The Ludwig Center and The Howard Hughes Medical Institute at Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland 21287, USA.
  • Kazazian HH; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
  • Solyom S; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;
Genome Res ; 25(10): 1536-45, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26260970

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Mutagénesis Insercional / Elementos de Nucleótido Esparcido Largo / Neoplasias Gastrointestinales Límite: Humans Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2015 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Mutagénesis Insercional / Elementos de Nucleótido Esparcido Largo / Neoplasias Gastrointestinales Límite: Humans Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2015 Tipo del documento: Article