Calculation of Cardiac Kinetic Energy Index from PET images.
Stud Health Technol Inform
; 216: 653-7, 2015.
Article
en En
| MEDLINE
| ID: mdl-26262132
ABSTRACT
Cardiac function can be assessed from displacement measurements in imaging modalities from nuclear medicine Using positron emission tomography (PET) image sequences with Rubidium-82, we propose and estimate the total Kinetic Energy Index (KEf) obtained from the velocity field, which was calculated using 3D optical flow(OF) methods applied over the temporal image sequence. However, it was found that the brightness of the image varied unexpectedly between frames, violating the constant brightness assumption of the OF method and causing large errors in estimating the velocity field. Therefore total brightness was equalized across image frames and the adjusted configuration tested with rest perfusion images acquired from individuals with normal (n=30) and low (n=33) cardiac function. For these images KEf was calculated as 0.5731±0.0899 and 0.3812±0.1146 for individuals with normal and low cardiac function respectively. The ability of KEf to properly classify patients into the two groups was tested with a ROC analysis, with area under the curve estimated as 0.906. To our knowledge this is the first time that KEf has been applied to PET images.
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Bases de datos:
MEDLINE
Asunto principal:
Volumen Sistólico
/
Interpretación de Imagen Asistida por Computador
/
Función Ventricular Izquierda
/
Tomografía de Emisión de Positrones
/
Transferencia de Energía
/
Ventrículos Cardíacos
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Stud Health Technol Inform
Asunto de la revista:
INFORMATICA MEDICA
/
PESQUISA EM SERVICOS DE SAUDE
Año:
2015
Tipo del documento:
Article
País de afiliación:
Brasil