Opinion of the scientific committee on consumer safety (SCCS)--2nd Revision of the safety of the use of poly(hexamethylene) biguanide hydrochloride or polyaminopropyl biguanide (PHMB) in cosmetic products.
Regul Toxicol Pharmacol
; 73(3): 885-6, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26456666
ABSTRACT
Conclusion of the opinion On the basis of the data available, the SCCS concludes that Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in cosmetic spray formulations and in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be based on a lower use concentration and/or restrictions with regard to cosmetic products' categories. Dermal absorption studies on additional representative cosmetic formulations are needed. PHMB is used in a variety of applications other than cosmetics. General exposure data from sources others than cosmetics should be submitted for the assessment of the aggregate exposure of PHMB.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Biguanidas
/
Seguridad de Productos para el Consumidor
/
Cosméticos
Tipo de estudio:
Etiology_studies
/
Guideline
/
Risk_factors_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Regul Toxicol Pharmacol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Alemania