Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression.

Xie, Tao; Musteanu, Monica; Lopez-Casas, Pedro P; Shields, David J; Olson, Peter; Rejto, Paul A; Hidalgo, Manuel

Xie, Tao; Musteanu, Monica; Lopez-Casas, Pedro P; Shields, David J; Olson, Peter; Rejto, Paul A; Hidalgo, Manuel.

Afiliación

Xie T; Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America.
Musteanu M; CNIO (Spanish National Cancer Research Centre), E-28029, Madrid, Madrid, Spain.
Lopez-Casas PP; CNIO (Spanish National Cancer Research Centre), E-28029, Madrid, Madrid, Spain.
Shields DJ; Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America.
Olson P; Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America.
Rejto PA; Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America.
Hidalgo M; CNIO (Spanish National Cancer Research Centre), E-28029, Madrid, Madrid, Spain.

PLoS One ; 10(11): e0142631, 2015.

Article en En | MEDLINE | ID: mdl-26555578

Asunto(s)

Carcinoma Ductal Pancreático/patología; Exoma; Neoplasias Pancreáticas/patología; Mutación Puntual; Anciano; Autopsia; Carcinoma Ductal Pancreático/genética; Progresión de la Enfermedad; Femenino; Xenoinjertos; Humanos; Masculino; Neoplasias Pancreáticas/genética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Mutación Puntual / Carcinoma Ductal Pancreático / Exoma Tipo de estudio: Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

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