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Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes.
Yeap, Leng-Siew; Hwang, Joyce K; Du, Zhou; Meyers, Robin M; Meng, Fei-Long; Jakubauskaite, Agne; Liu, Mengyuan; Mani, Vinidhra; Neuberg, Donna; Kepler, Thomas B; Wang, Jing H; Alt, Frederick W.
Afiliación
  • Yeap LS; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Hwang JK; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Du Z; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Meyers RM; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Meng FL; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Jakubauskaite A; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Liu M; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Mani V; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Neuberg D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Kepler TB; Department of Microbiology, Boston University School of Medicine, Boston, MA 02215, USA.
  • Wang JH; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Alt FW; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine at Boston Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: alt@enders.tch.harvard.edu.
Cell ; 163(5): 1124-1137, 2015 Nov 19.
Article en En | MEDLINE | ID: mdl-26582132
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa / Hipermutación Somática de Inmunoglobulina / Recombinación V(D)J Límite: Animals / Humans Idioma: En Revista: Cell Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa / Hipermutación Somática de Inmunoglobulina / Recombinación V(D)J Límite: Animals / Humans Idioma: En Revista: Cell Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos