Integrating smoking cessation into routine care in hospitals--a randomized controlled trial.
Addiction
; 111(4): 714-23, 2016 Apr.
Article
en En
| MEDLINE
| ID: mdl-26597421
ABSTRACT
AIMS:
To evaluate the effectiveness of a pharmacist-led multi-component smoking cessation programme (GIVE UP FOR GOOD) compared with usual care in hospitalized smokers.DESIGN:
Randomized, assessor-blinded, parallel-group trial.SETTING:
Three tertiary public hospitals in Australia.PARTICIPANTS:
A total of 600 adult in-patient smokers [mean ± standard deviation (SD), age 51 ± 14 years; 64% male] available for 12 months follow-up.INTERVENTIONS:
Multi-component hospital pharmacist-led behavioural counselling and/or pharmacotherapy provided during hospital stay, on discharge and 1 month post-discharge, with further support involving community health professionals (n = 300). Usual care comprised routine care provided by hospitals (n = 300). MEASUREMENTS Two primary end-points were tested using intention-to-treatanalysis:
carbon monoxide (CO)-validated 1-month sustained abstinence at 6-month follow-up and verified 6-month sustained abstinence at 12-month follow-up. Smoking status and pharmacotherapy usage were assessed at baseline, discharge, 1, 6 and 12 months.FINDINGS:
Sustained abstinence rates for intervention and control groups were not significantly different at both 6 months [11.6% (34 of 294) versus 12.6% (37 of 294); odds ratio (OR) = 0.91, 95% confidence interval (CI) = 0.55-1.50] and 12 months [11.6% (34 of 292) versus 11.2% (33 of 294); OR = 1.04, 95% CI = 0.63-1.73]. Secondary end-points, self-reported continuous abstinence at 6 and 12 months, also agreed with the primary end-points. Use of pharmacotherapy was higher in the intervention group, both during hospital stay [52.3% (157 of 300) versus 42.7% (128 of 300); P = 0.016] and after discharge [59.6% (174 of 292) versus 43.5% (128 of 294); P < 0.001].CONCLUSIONS:
A pharmacist-led multi-component smoking cessation intervention provided during hospital stay did not improve sustained abstinence rates at either 6 or 12 months compared with routine hospital care.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tabaquismo
/
Cese del Hábito de Fumar
/
Consejo
/
Dispositivos para Dejar de Fumar Tabaco
/
Pacientes Internos
Tipo de estudio:
Clinical_trials
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Humans
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Addiction
Asunto de la revista:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Año:
2016
Tipo del documento:
Article
País de afiliación:
Australia