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Synthesis and multiparametric evaluation of thiadiazoles and oxadiazoles as diacylglycerol acyltransferase type 1 inhibitors.
Mougenot, Patrick; Namane, Claudie; Fett, Eykmar; Goumy, Florence; Dadji-Faïhun, Rommel; Langot, Gwladys; Monseau, Catherine; Onofri, Bénédicte; Pacquet, François; Pascal, Cécile; Crespin, Olivier; Ben-Hassine, Majdi; Ragot, Jean-Luc; Van-Pham, Thao; Philippo, Christophe; Chatelain-Egger, Florence; Péron, Philippe; Le Bail, Jean-Christophe; Guillot, Etienne; Chamiot-Clerc, Philippe; Chabanaud, Marie-Aude; Pruniaux, Marie-Pierre; Ménegotto, Jérôme; Schmidt, Friedemann; Venier, Olivier; Viviani, Fabrice; Nicolai, Eric.
Afiliación
  • Mougenot P; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Namane C; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Fett E; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Goumy F; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Dadji-Faïhun R; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Langot G; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Monseau C; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Onofri B; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Pacquet F; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Pascal C; Sanofi-aventis R&D, 69280 Marcy-l'Etoile, France.
  • Crespin O; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Ben-Hassine M; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Ragot JL; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Van-Pham T; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Philippo C; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Chatelain-Egger F; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Péron P; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Le Bail JC; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Guillot E; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Chamiot-Clerc P; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Chabanaud MA; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Pruniaux MP; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Ménegotto J; Evotec, 31036 Toulouse, France.
  • Schmidt F; Sanofi-aventis Deutschland GmbH, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.
  • Venier O; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
  • Viviani F; GlaxoSmithKline, 91951 Les Ulis, France.
  • Nicolai E; Sanofi-aventis R&D, 91385 Chilly-Mazarin, France.
Bioorg Med Chem Lett ; 26(1): 25-32, 2016 Jan 01.
Article en En | MEDLINE | ID: mdl-26627579
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxadiazoles / Tiadiazoles / Inhibidores Enzimáticos / Diacilglicerol O-Acetiltransferasa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxadiazoles / Tiadiazoles / Inhibidores Enzimáticos / Diacilglicerol O-Acetiltransferasa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Francia