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Two New Flavonol Glycosides from Polygala sibirica L. var megalopha Fr.
Huang, Yan-Jie; Zhou, Ling-Yun; Wang, Jun-Min; Li, Qiang; Geng, Yuan-Yuan; Liu, Hai-Yang; Hua, Yan.
Afiliación
  • Huang YJ; College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China. hyj0106@foxmail.com.
  • Zhou LY; College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China. zly324@foxmail.com.
  • Wang JM; School of Pharmacy, Wannan Medical College, Wuhu 241002, Anhui, China. zly324@foxmail.com.
  • Li Q; College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China. dawn723@163.com.
  • Geng YY; College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China. kib312270163@foxmail.com.
  • Liu HY; College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China. 18208826431@163.com.
  • Hua Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China. haiyangliu@mail.kib.ac.cn.
Molecules ; 20(12): 21494-500, 2015 Dec 02.
Article en En | MEDLINE | ID: mdl-26633343
Two new flavonol glycosides, named polygalin H (1) and polygalin I (2), as well as the known compound polygalin D (3), were isolated from the whole plant of Polygala sibirica L. var megalopha Fr. Their structures were elucidated on the basis of spectroscopic data analysis. These flavonol glycosides exhibited strong inhibitory activities against xanthine oxidase in vitro. Their half-maximal inhibitory concentrations (IC50) were calculated, which were 9.48, 8.31, 16.00 µM, respectively.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Xantina Oxidasa / Extractos Vegetales / Polygala / Flavonoles / Inhibidores Enzimáticos / Glicósidos Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Xantina Oxidasa / Extractos Vegetales / Polygala / Flavonoles / Inhibidores Enzimáticos / Glicósidos Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China