Recurrent wheezing and asthma after bocavirus bronchiolitis.
Allergol Immunopathol (Madr)
; 44(5): 410-4, 2016.
Article
en En
| MEDLINE
| ID: mdl-26657170
ABSTRACT
BACKGROUND:
Human bocavirus (HBoV) was recently discovered and identified as an important cause of respiratory infection in young children. However, the relationship between HBoV-bronchiolitis and the development of recurrent wheezing has not yet been established.OBJECTIVE:
We designed this study in order to describe the mid-term outcome, regarding the development of recurrent wheezing and asthma of HBoV-bronchiolitis patients and to compare it with RSV-bronchiolitis infants.METHODS:
We studied 80 children (10 with HBoV and 70 with RSV infection), currently aged ≥4 years and previously hospitalised during the seasons 2004-2009 due to acute bronchiolitis. Epidemiological and clinical data were collected through structured clinical interviews at the follow-up visit. Spirometry and skin prick tests to common food and inhaled allergens were performed.RESULTS:
All HBoV-patients developed recurrent wheezing and half of them had asthma at age 5-7 years. Almost 30% required hospital admission for recurrent wheezing. Asthma (odds ratio (OR)=1.28) and current asthma (OR=2.18) were significantly more frequent in children with HBoV-bronchiolitis than in RSV-bronchiolitis. FEV1 values were 99.2±4.8 in HBoV-group vs. 103±11 in RSV-group, p 0.09. No differences were found with respect to allergic rhinitis, atopic dermatitis, food allergy, proportion of positive prick tests, and family history of atopy or asthma.CONCLUSIONS:
Severe HBoV-bronchiolitis in infancy was strongly associated with asthma at 5-7 years.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Asma
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Bronquiolitis Viral
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Ruidos Respiratorios
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Virus Sincitial Respiratorio Humano
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Infecciones por Virus Sincitial Respiratorio
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Infecciones por Parvoviridae
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Bocavirus Humano
Tipo de estudio:
Observational_studies
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Prognostic_studies
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Qualitative_research
/
Risk_factors_studies
Límite:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Revista:
Allergol Immunopathol (Madr)
Año:
2016
Tipo del documento:
Article
País de afiliación:
España