The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells.

Notaro, Antonietta; Sabella, Selenia; Pellerito, Ornella; Vento, Renza; Calvaruso, Giuseppe; Giuliano, Michela

Notaro, Antonietta; Sabella, Selenia; Pellerito, Ornella; Vento, Renza; Calvaruso, Giuseppe; Giuliano, Michela.

Afiliación

Notaro A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Laboratory of Biochemistry, University of Palermo, Polyclinic, Palermo 90128, Italy.
Sabella S; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Laboratory of Biochemistry, University of Palermo, Polyclinic, Palermo 90128, Italy.
Pellerito O; Department of Genetics and Development, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada.
Vento R; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Laboratory of Biochemistry, University of Palermo, Polyclinic, Palermo 90128, Italy.
Calvaruso G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Laboratory of Biochemistry, University of Palermo, Polyclinic, Palermo 90128, Italy.
Giuliano M; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Laboratory of Biochemistry, University of Palermo, Polyclinic, Palermo 90128, Italy.

Int J Oncol ; 48(3): 1039-44, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26698404

Asunto(s)

Neoplasias Óseas/metabolismo; Osteonectina/metabolismo; Osteosarcoma/metabolismo; Ligando Inductor de Apoptosis Relacionado con TNF/metabolismo; Apoptosis; Benzoxazinas/química; Neoplasias Óseas/patología; Caspasa 8/metabolismo; Muerte Celular; Línea Celular Tumoral; Membrana Celular/metabolismo; Supervivencia Celular; Estrés del Retículo Endoplásmico; Silenciador del Gen; Humanos; Morfolinas/química; Naftalenos/química; Osteosarcoma/patología; Dominios Proteicos; Interferencia de ARN

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma / Osteonectina / Ligando Inductor de Apoptosis Relacionado con TNF Límite: Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Italia

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