Catalytic insertion of aldehydes into dihalonitroacetophenones via sequential bond scission-aldol reaction-acyl transfer.
Chem Commun (Camb)
; 52(17): 3576-9, 2016 Feb 28.
Article
en En
| MEDLINE
| ID: mdl-26846436
ABSTRACT
A catalytic process that provides dihalogenated nitro alcohols in up to 99% yield and with 100% atom economy is described. In situ cleavage of dihalonitroacetophenones affords nitronates that undergo Lewis acid catalyzed addition to aldehydes. Final benzoylation renders the sequence irreversible and regenerates the bond scission and acyl transfer agent.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Acetofenonas
/
Aldehídos
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos