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Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.
Kim, Nayoung; Cho, Ahye; Watanabe, Hideo; Choi, Yoon-La; Aziz, Meraj; Kassner, Michelle; Joung, Je-Gun; Park, Angela Kyung-Joo; Francis, Joshua M; Bae, Joon Seol; Ahn, Soo-Min; Kim, Kyoung-Mee; Park, Joon Oh; Park, Woong-Yang; Ahn, Myung-Ju; Park, Keunchil; Koo, Jaehyung; Yin, Hongwei Holly; Cho, Jeonghee.
Afiliación
  • Kim N; Department of NanoBio Medical Science, Dankook University, Cheonan 31116, Republic of Korea.
  • Cho A; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 135-967, Republic of Korea.
  • Watanabe H; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 135-967, Republic of Korea.
  • Choi YL; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York, NY 10029, USA.
  • Aziz M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Kassner M; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 135-967, Republic of Korea.
  • Joung JG; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-967, Republic of Korea.
  • Park AK; Cancer and Cell Biology Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.
  • Francis JM; Cancer and Cell Biology Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.
  • Bae JS; Samsung Genome Institute, Samsung Medical Center, Seoul 135-967, Republic of Korea.
  • Ahn SM; Department of NanoBio Medical Science, Dankook University, Cheonan 31116, Republic of Korea.
  • Kim KM; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 135-967, Republic of Korea.
  • Park JO; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  • Park WY; Samsung Genome Institute, Samsung Medical Center, Seoul 135-967, Republic of Korea.
  • Ahn MJ; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-967, Republic of Korea.
  • Park K; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-967, Republic of Korea.
  • Koo J; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-967, Republic of Korea.
  • Yin HH; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 135-967, Republic of Korea.
  • Cho J; Samsung Genome Institute, Samsung Medical Center, Seoul 135-967, Republic of Korea.
Oncotarget ; 7(12): 13797-809, 2016 Mar 22.
Article en En | MEDLINE | ID: mdl-26883194
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Genómica / Receptores ErbB / Clorhidrato de Erlotinib / Neoplasias Pulmonares / Mutación / Proteínas del Tejido Nervioso Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Genómica / Receptores ErbB / Clorhidrato de Erlotinib / Neoplasias Pulmonares / Mutación / Proteínas del Tejido Nervioso Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article