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Cost-effectiveness of a risk-based secondary screening programme of type 2 diabetes.
Nagy, Balázs; Zsólyom, Adriána; Nagyjánosi, László; Merész, Gergo; Steiner, Tamás; Papp, Eszter; Dessewffy, Zoltán; Jermendy, György; Winkler, Gábor; Kaló, Zoltán; Vokó, Zoltán.
Afiliación
  • Nagy B; Syreon Research Institute, Budapest, Hungary. balazsnagy@caesar.elte.hu.
  • Zsólyom A; Department of Health Policy and Health Economics, Eötvös Loránd University, Budapest, Hungary. balazsnagy@caesar.elte.hu.
  • Nagyjánosi L; Syreon Research Institute, Budapest, Hungary.
  • Merész G; Faculty of Social Sciences, Social Policy Ph.D. Programme, Eötvös Loránd University, Budapest, Hungary.
  • Steiner T; Health Sciences Doctoral School, University of Debrecen, Debrecen, Hungary.
  • Papp E; Syreon Research Institute, Budapest, Hungary.
  • Dessewffy Z; Faculty of Social Sciences, Social Policy Ph.D. Programme, Eötvös Loránd University, Budapest, Hungary.
  • Jermendy G; 2nd Department of Internal Medicine-Diabetology, St. John's Hospital and North-Buda United Institutions, Budapest, Hungary.
  • Winkler G; Department of Endocrinology, St. Christopher's Clinic, Budapest, Hungary.
  • Kaló Z; National Institute of Pharmacy and Nutrition, Budapest, Hungary.
  • Vokó Z; Novartis Hungary, Budapest, Hungary.
Diabetes Metab Res Rev ; 32(7): 710-729, 2016 10.
Article en En | MEDLINE | ID: mdl-26888326
OBJECTIVE: The objective of this study was to develop a long-term economic model for type 2 diabetes to describe the entire spectrum of the disease over a wide range of healthcare programmes. The model evaluates a public health, risk-based screening programme in a country specific setting. METHODS: The lifespan of persons and important phases of the disease and related interventions are recorded in a Markov model, which first simulates the effect of screening, then replicates important complications of diabetes, follows the progression of individuals through physiological variables and finally calculates outcomes in monetary and naturalistic units. RESULTS: The introduction of the screening programme nearly doubled the proportion of diagnosed patients at the age of 50 and prolonged life expectancy. Three-yearly screening gained 0.0229 quality adjusted life years for an additional €83 per person compared with no screening and resulted an incremental cost-effectiveness ratio of €3630/quality adjusted life years. CONCLUSION: From the economic perspective introduction of the 3-yearly screening programme is justifiable and it provides a good value for money. Copyright © 2016 John Wiley & Sons, Ltd.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tamizaje Masivo / Análisis Costo-Beneficio / Años de Vida Ajustados por Calidad de Vida / Diabetes Mellitus Tipo 2 / Hipoglucemiantes Tipo de estudio: Diagnostic_studies / Etiology_studies / Health_economic_evaluation / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Metab Res Rev Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2016 Tipo del documento: Article País de afiliación: Hungria

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tamizaje Masivo / Análisis Costo-Beneficio / Años de Vida Ajustados por Calidad de Vida / Diabetes Mellitus Tipo 2 / Hipoglucemiantes Tipo de estudio: Diagnostic_studies / Etiology_studies / Health_economic_evaluation / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Metab Res Rev Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2016 Tipo del documento: Article País de afiliación: Hungria