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Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.
Hubbard, Nicholas; Hagin, David; Sommer, Karen; Song, Yumei; Khan, Iram; Clough, Courtnee; Ochs, Hans D; Rawlings, David J; Scharenberg, Andrew M; Torgerson, Troy R.
Afiliación
  • Hubbard N; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Hagin D; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Sommer K; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Song Y; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Khan I; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Clough C; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and.
  • Ochs HD; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and Department of Pediatrics and.
  • Rawlings DJ; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and Department of Pediatrics and Department of Immunology, University of Washington, Seattle, WA.
  • Scharenberg AM; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and Department of Pediatrics and Department of Immunology, University of Washington, Seattle, WA.
  • Torgerson TR; Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and Department of Pediatrics and.
Blood ; 127(21): 2513-22, 2016 05 26.
Article en En | MEDLINE | ID: mdl-26903548
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Linfocitos T / Regulación de la Expresión Génica / Ligando de CD40 / Síndrome de Inmunodeficiencia con Hiper-IgM Tipo 1 / Reparación del Gen Blanco / Edición Génica Límite: Animals / Female / Humans / Male Idioma: En Revista: Blood Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Linfocitos T / Regulación de la Expresión Génica / Ligando de CD40 / Síndrome de Inmunodeficiencia con Hiper-IgM Tipo 1 / Reparación del Gen Blanco / Edición Génica Límite: Animals / Female / Humans / Male Idioma: En Revista: Blood Año: 2016 Tipo del documento: Article