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Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.
de Leng, Wendy W J; Gadellaa-van Hooijdonk, Christa G; Barendregt-Smouter, Françoise A S; Koudijs, Marco J; Nijman, Ies; Hinrichs, John W J; Cuppen, Edwin; van Lieshout, Stef; Loberg, Robert D; de Jonge, Maja; Voest, Emile E; de Weger, Roel A; Steeghs, Neeltje; Langenberg, Marlies H G; Sleijfer, Stefan; Willems, Stefan M; Lolkema, Martijn P.
Afiliación
  • de Leng WW; Department of Pathology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Gadellaa-van Hooijdonk CG; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Barendregt-Smouter FA; Department of Medical Oncology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Koudijs MJ; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Nijman I; Department of Medical Genetics, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Hinrichs JW; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Cuppen E; Department of Medical Genetics, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • van Lieshout S; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Loberg RD; Department of Medical Genetics, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • de Jonge M; Department of Pathology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Voest EE; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • de Weger RA; Department of Medical Genetics, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Steeghs N; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Langenberg MH; Department of Medical Genetics, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
  • Sleijfer S; Medical Sciences, Amgen Inc., Thousand Oaks, CA, 91320-1799, United States of America.
  • Willems SM; Netherlands Center for Personalized Cancer Treatment, Utrecht, The Netherlands.
  • Lolkema MP; Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics Netherlands, 3075 EA Rotterdam, The Netherlands.
PLoS One ; 11(2): e0149405, 2016.
Article en En | MEDLINE | ID: mdl-26919633
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Análisis Mutacional de ADN / Secuenciación de Nucleótidos de Alto Rendimiento / Mutación / Neoplasias Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Análisis Mutacional de ADN / Secuenciación de Nucleótidos de Alto Rendimiento / Mutación / Neoplasias Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos