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Lethal acute liver failure in a patient treated with sunitinib.
Guillen, S S; Meijer, M; de Jongh, F E.
Afiliación
  • Guillen SS; Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
  • Meijer M; Department of Medical Oncology, Erasmus MC Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands.
  • de Jongh FE; Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
BMJ Case Rep ; 20162016 Mar 01.
Article en En | MEDLINE | ID: mdl-26933184
Sunitinib is a tyrosine kinase inhibitor that is used as an anticancer drug in renal cell carcinoma (RCC), pancreatic neuroendocrine tumours (PNETs) and gastrointestinal stromal tumour. Elevated liver enzymes are frequently observed during treatment but acute liver failure is uncommon. We describe a case of fulminant acute liver failure and acute kidney injury during treatment with sunitinib for metastatic RCC.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Fallo Hepático Agudo / Inhibidores de Proteínas Quinasas / Lesión Renal Aguda / Indoles Límite: Aged / Humans / Male Idioma: En Revista: BMJ Case Rep Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Fallo Hepático Agudo / Inhibidores de Proteínas Quinasas / Lesión Renal Aguda / Indoles Límite: Aged / Humans / Male Idioma: En Revista: BMJ Case Rep Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos