Tenofovir alafenamide as part of a salvage regimen in a patient with multi-drug resistant HIV and tenofovir-DF-associated renal tubulopathy.
Antivir Ther
; 21(6): 553-558, 2016.
Article
en En
| MEDLINE
| ID: mdl-26954372
ABSTRACT
We describe a patient with two recent episodes of tenofovir disoproxil fumarate (TDF)-associated acute kidney injury and six-class drug-resistant HIV infection who achieved and maintained viral suppression without worsening kidney function on a regimen including tenofovir alafenamide (TAF) through 48 weeks of therapy. The safety and efficacy of TAF in patients with TDF-associated renal tubulopathy and multiple drug resistant HIV has not yet been described. TAF may represent a useful option to maximally suppress HIV in patients with these complications.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Adenina
/
Infecciones por VIH
/
Fármacos Anti-VIH
/
Lesión Renal Aguda
/
Tenofovir
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Antivir Ther
Asunto de la revista:
TERAPIA POR MEDICAMENTOS
/
VIROLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos