Possible roles of platelet-derived microparticles in atherosclerosis.

Wang, Zhi-Ting; Wang, Zi; Hu, Yan-Wei

Wang, Zhi-Ting; Wang, Zi; Hu, Yan-Wei.

Afiliación

Wang ZT; Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Wang Z; School of Pharmacy, Fudan University, Shanghai 201203, China.
Hu YW; Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address: ywhu0618@163.com.

Atherosclerosis ; 248: 10-6, 2016 May.

Article en En | MEDLINE | ID: mdl-26978582

ABSTRACT

ABSTRACT

Platelets and platelet-derived microparticles (PMPs) play important roles in cardiovascular diseases, especially atherosclerosis. Continued research has revealed that PMPs have numerous functions in atherosclerosis, not only in thrombosis formation, but also by induction of inflammation. PMPs also induce formation of foam cells. Recent evidence strongly indicates a significant role of PMPs in atherosclerosis. Here, current research on the function of PMPs in atherosclerosis is reviewed.

Asunto(s)

Aterosclerosis/sangre; Plaquetas/citología; Micropartículas Derivadas de Células/metabolismo; Biomarcadores/metabolismo; Coagulación Sanguínea; Adhesión Celular; Células Espumosas/citología; Humanos; Inflamación; Metabolismo de los Lípidos; Lípidos/química; Neoplasias/metabolismo; Activación Plaquetaria

Palabras clave

Atherosclerosis; Foam cells; Inflammation; PMPs; Thrombosis formation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaquetas / Aterosclerosis / Micropartículas Derivadas de Células Límite: Humans Idioma: En Revista: Atherosclerosis Año: 2016 Tipo del documento: Article País de afiliación: China

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