Significance of TNF-α and IL-6 expression in invasive pituitary adenomas.
Genet Mol Res
; 15(1)2016 Mar 22.
Article
en En
| MEDLINE
| ID: mdl-27050975
ABSTRACT
The aim of this study was to investigate expression of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in invasive pituitary adenomas (IPAs). The streptavidin peroxidase immunohistochemical method was employed to detect their expression in 40 cases of IPA and 40 of non-invasive pituitary adenoma (NIPA). TNF-α and IL-6 were found to be upregulated in IPA tissue compared with that of NIPA (P < 0.05). These proteins may therefore play important roles in the occurrence and progression of IPA.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Hipofisarias
/
Interleucina-6
/
Factor de Necrosis Tumoral alfa
Límite:
Humans
Idioma:
En
Revista:
Genet Mol Res
Asunto de la revista:
BIOLOGIA MOLECULAR
/
GENETICA
Año:
2016
Tipo del documento:
Article
País de afiliación:
China