Teenage girls with type 1 diabetes have poorer metabolic control than boys and face more complications in early adulthood.
J Diabetes Complications
; 30(5): 917-22, 2016 07.
Article
en En
| MEDLINE
| ID: mdl-27052153
ABSTRACT
AIMS:
To compare metabolic control between males and females with type 1 diabetes during adolescence and as young adults, and relate it to microvascular complications.METHODS:
Data concerning 4000 adolescents with type 1 diabetes registered in the Swedish paediatric diabetes quality registry, and above the age of 18years in the Swedish National Diabetes Registry was used.RESULTS:
When dividing HbA1c values in three groups; < 7.4% (57mmol/mol), 7.4-9.3% (57-78mmol/mol) and >9.3% (78mmol/mol), there was a higher proportion of females in the highest group during adolescence. In the group with the highest HbA1c values during adolescence and as adults, 51.7% were females, expected value 46.2%; in the group with low HbA1c values in both registries, 34.2% were females, p<0.001. As adults, more females had retinopathy, p<0.05. Females had higher mean HbA1c values at diagnosis, 11.2 vs. 10.9% (99 vs. 96mmol/mol), p<0.03, during adolescence, 8.5 vs. 8.2% (69 vs. 66mmol/mol) p<0.01, but not as young adults.CONCLUSIONS:
Worse glycaemic control was found in adolescent females, and they had a higher frequency of microvascular complications. Improved paediatric diabetes care is of great importance for increasing the likelihood of lower mortality and morbidity later in life.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus Tipo 1
/
Angiopatías Diabéticas
/
Nefropatías Diabéticas
/
Hiperglucemia
/
Hipoglucemia
/
Hipoglucemiantes
/
Insulina
Tipo de estudio:
Etiology_studies
/
Observational_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Diabetes Complications
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Suecia