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Species Differences in the Oxidative Desulfurization of a Thiouracil-Based Irreversible Myeloperoxidase Inactivator by Flavin-Containing Monooxygenase Enzymes.
Eng, Heather; Sharma, Raman; Wolford, Angela; Di, Li; Ruggeri, Roger B; Buckbinder, Leonard; Conn, Edward L; Dalvie, Deepak K; Kalgutkar, Amit S.
Afiliación
  • Eng H; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Sharma R; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Wolford A; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Di L; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Ruggeri RB; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Buckbinder L; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Conn EL; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Dalvie DK; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
  • Kalgutkar AS; Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., Groton, Connecticut (H.E., R.S., A.W., L.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department, Pfizer Inc., La Jolla, California (D.K.D.); Pharmacokinetics, Pharmacodynamics, and Metabolism Department (A.S.K.),
Drug Metab Dispos ; 44(8): 1262-9, 2016 08.
Article en En | MEDLINE | ID: mdl-27079250
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxigenasas / Tiouracilo / Peroxidasa / Inhibidores Enzimáticos / Hígado Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxigenasas / Tiouracilo / Peroxidasa / Inhibidores Enzimáticos / Hígado Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article